目的: 对比中药金刚藤+甲氨蝶呤+米非司酮与甲氨蝶呤+米非司酮保守治疗异位妊娠包块的疗效。
方法: 选取内蒙古医科大学附属医院妇产科2007－1 ～ 2011－1 住院行保守治疗的异位妊娠病人90 例随机分为实
验组45 例和对照组45 例。实验组给予金刚藤+ 米非司酮+ 甲氨蝶呤治疗，对照组给予米非司酮+甲氨蝶呤治
疗，比较两组的疗效。统计分析采用SPSS 13． 0 软件。结果: 治疗后实验组血清β－HCG 恢复至正常时间、包块
吸收时间及输卵管复通率分别为16． 13 ±8． 13 d、30． 46 ±7． 56 d 和80%，而对照组分别为22． 05 ±7． 15 d、39． 99
±18． 26 d 和75%，两组差异均有统计学意义，而两组在有效率［95． 56%( 43 /45) vs． 94%( 47 /50) ］和药物副反应发生率方面，差
异无统计学意义。结论: 金刚藤辅助治疗异位妊娠在缩短血清β－HCG 恢复至正常时间和包块吸收时间，以及改
善输卵管功能方面均有明显作用。

Objective: To compare the clinical efficacy of conservative treatment of Jingangteng，
Methotrexate and Mifepristone to Mifepristone and Methotrexate for masses of ectopic pregnancy． Methods:
90 patients with conservative treatment of ectopic pregnancy were randomly divided into two
groups，which from January 2007 to January 2011 in the Affiliated Hospital of Inner Mongolia Medical
University． 45 cases of these patients with Jingangteng，Methotrexate and Mifepristone therapy as experimental
group，other 45 cases treated with Mifepristone and Methotrexate for control group． SPSS 13． 0
for Statistical analysis． Result: After treatment the time of blood HCG － βdropped to normal range，
masses absorption and fallopian tube repatency is 16． 13±8． 13 d、30． 46±7． 56 d and 80% in experimental
group，while it is 22． 05±7． 15 d， 39． 99±18． 26 d and 75%in control group， the difference has
statistical significance，but between two groups the differences of effective rate［95． 56%( 43 /45) vs． 94%47 /50］and
side effects has no statistical significance． Conclusion: The combination of Jingangteng is much more
effective in shorten time of blood HCG－βback to normal，masses absorption and fallopian tube repatency．

R984

 收稿日期: 2012－12－25; 修回日期: 2013－04－10
基金项目: 内蒙古教育厅科研项目( NJ10145)
作者简介: 李国慧( 1961－) ，女，内蒙古医科大学附属医院妇科主任医师。