[关键词]
[摘要]
目的:观察放疗联合热疗治疗原发灶不同的颈部淋巴结转移癌的临床疗效。方法:回顾性分析了我
科60例来源于鼻咽癌、扁桃体癌、梨状窝癌、乳腺癌、喉癌、食管癌及肺癌的颈部淋巴结转移癌病人资料,放疗加
热疗组(R+H)28例,单纯放疗组(R)32例。放疗总量60~70Gy/6~7wk,5次/wk;微波热疗2次/wk。随访
3mo,观察近期疗效。结果:治疗结束时:放疗加热疗组CR 82.1%,单纯放疗组CR 为34.4%,两组比较差异明
显(P<0.05);前者的总有效率(CR+PR)96.4%,后者的(CR+PR)为59.3%,两组比较差异有显著性(P<
0.05)。疗后3mo时:放疗加热疗组CR 89.3%,单纯放疗组CR为50%,两组比较差异明显(P<0.05);前者的
(CR+PR)为96.4%,后者的(CR+PR)为68.8%,两组比较差异有显著性(P<0.05)。结论:微波热疗对放疗有
协同作用,二者配合对颈部淋巴结转移癌的治疗有明显的临床应用价值。
[Key word]
[Abstract]
Objective:To observe the efficacy to malignant tumors migrated to neck lymph
nodes treated by radiotherapy combined with hyperthermia.Methods:Sixty patients diagnosed
as nasopharyngeal carcinoma,tonsil cancer,pyriform sinus carcinoma,breast cancer,larynx carcinoma,
esophagus carcinoma,lung cancer which have migrated to neck lymph node were divided
to radiotherapy combined with microwave hyperthermia(R+H)group and alone radiotherapy(
R)group.Radiotherapy DT were 60-70Gy,five times a week,microwave hyperthermia
were used two times a week.All patients were followed-up for 3months and observed the efficacy.
Results:At the end of treatment in the R + H group,complete response rate(CR)was
82.1%(23/28),where as in R group,complete response rate was 34.4%(11/32),(P<0.05).
In R + H group,the total effective rate(CR + PR)was 96.4%(27/28),where as in R group,
the total effective rate was 59.3%(19/32)(P<0.05).Follow up at 3months after treatment,inthe R + H group,complete response rate(CR)was 89.3%(25/28),where as in R group,complete
response rate was 50%(16/32)(P<0.05).In R+ H group,the total effective rate(CR+
PR)was 96.4%(27/28),where as in R group,the total effective rate was 68.8%(22/32)(P<
0.05).There was obvious difference in response between the two groups(P<0.05).Conclusions:
Microwave hyperthermia to radiotherapy have a synergistic effect,two combination of
these two on the neck of lymph node metastasis cancer treatment has important clinical application
value.
[中图分类号]
R739.91
[基金项目]
收稿日期:2013-06-05;修回日期:2013-08-24
基金项目:内蒙古自然科学基金(2010MS1145)
作者简介:秦晓玲(1975-),女,内蒙古医科大学附属医院放疗科主治医师,医学硕士。
通讯作者:郁志龙,主任医师,E-mail:Richard_yu1961269@sina.com内蒙古医科大学附属医院放疗科,010050