目的: 确定XE－2100 血液分析仪测定新生儿网织红细胞的参考值。方法: 以XE－2100 血液分析仪
测定146 例( 男72 例，女74 例) 出生3 ～ 7 d 的新生儿的网织红细胞的百分率( RET%) 、网织红细胞的绝对数
( RET#) 、未成熟网织红细胞指数( IRF) 及低荧光强度网织红细胞百分率( LFR%) ，中荧光强度网织红细胞
( MFR%) 、高光强度网织红细胞( HFR%) 通过统计学方法计算，确定其正常参考值范围。结果: RET%: 男性
为3． 12±0． 46，女性为3． 08±0． 47，男女比较两者无显著性差异( P＞0． 05) ; 合并后RET% 为3． 19±0． 47。RET#:
男性为147． 3±13． 6，女性为155． 8 ±14． 1，两者比较无显著性差异( P＜0． 05) 。IRF: 男性为21． 55 ±2． 09，女性
为23． 59±2． 26。LFR%: 男性为76． 49 ±2． 81; 女性为73． 64 ±2． 42。MFR% 男性为20． 05 ±1． 79，女性为18． 59
±2． 06; HFR%男性为3． 75±0． 09，女性为3． 98±0． 16． 结论: XE－2100 血液分析仪测新生儿网织红细胞参考值范
围与文献报道有所差异，新生儿RET#男、女无显著性差异。网织红细胞分群与性别无关。各实验室应根据自己
实验室仪器，确定本实验室的参考值范围。

Objective: To detect the reference range of Reticulocyte for neonates using XE－2100
automatic hematology analyzer． Methods: XE－2100 automatic hematology analyzer was used to detect
Ret%，RET#， IRF%，LRF%and MFR%from 146 cases of neonates，which were composed by 72 cases
of male neonates and 74 cases of female neonates． Suitable statistical analysis methods were employed
to establish the normal reference ranges． Results: For RET%， there was significant difference between
male and females neonates( 3． 12 ±0． 46 vs 3． 08 ±0． 47，P ＞0． 05) ，and mean range for RET% was
3． 19±0． 47． For RET#， there was no significant difference between male and females neonates( 147． 3
±13． 6 vs 155． 8±14． 1，P＞0． 05) ． The reference ranges of IRF for male neonates and female neonates
were 21． 55±2． 09 and 23． 59 ±2． 26， respectively． The reference ranges of LFR% for male neonates
and female neonates were 76． 49±2． 81 and 73． 64±2． 42， respectively． The reference ranges of MFR
for male neonates and female neonates were 20． 05 ±1． 79 and 18． 59 ±2． 06，respectively． The
reference ranges of HFR for male neonates and female neonates were 3． 75 ±0． 09 and 3． 98 ±0． 16．
Conclusions: The obtained reference ranges of reticulocyte for neonates using XE－2100 automatic hematology
analyzer were not consistent with those reported in previous studies，but there is not significant
differences in RET# between male neonates and female neonates． Reticulocyte grouping was not correlated
with gender． Each laboratory should determine their own reference ranges based on the instruments
used．

R446． 11

 收稿日期: 2013－08－30; 修回日期: 2013－11－16
基金项目: 内蒙古自治区教育厅基金( NJZZ13411)
作者简介: 杜肖彦( 1964－) ，女，内蒙古医科大学附属医院检验科副主任检验师。
通讯作者: 董莉，主任检验师，E－mail: dongsuanzhi@163． com． 内蒙古医科大学附属医院检验科， 010050