目的: 确立调律滴丸的最佳制备工艺。方法: 采用正交试验法，以基质种类、药物与基质配比、药液
温度、冷凝液温度作为考察因素进行正交试验，用3 个指标评定工艺的优劣。结果: 最佳制备工艺条件为: 以
PEG 4000 为基质，药物与基质配比为1: 2． 5，药液温度为85℃，冷凝液温度为12℃ ～ 14℃。结论: 优选得到的工
艺简便易行，有良好的重现性和可操作性。

Objective: To establish the optimized preparation process of Tiaolv guttate pills． Methods:
Orthogonal design was applied． Using the kind of base， ratio between drug and base， the temperature
of drug solution and the temperature of condensate liquid as affecting factors， the orthogonal test
was conducted， to assess the preparation process good or bad in the three indexes． Results: The optimized
preparation process was as follows: PEG 4000 was optimal bases， ratio between drug and base
was 1 ∶ 2． 5， the temperature of drug solution was 85℃， the temperature of condensate liquid was 12℃
～ 14℃． Conclusion: The optimized preparation process is simple and practicable，with good reproducibility．

R943． 1

 收稿日期: 2013－09－15; 修回日期: 2013－11－17
基金项目: 内蒙古自治区科技计划( 社发) 项目( 2011)
作者简介: 景舒( 1956－) ，女，内蒙古医科大学药学院药剂学教研室教授。