目的: 考察木香挥发油六个化学组分在其β－CD 包合物中的转移率。方法: 采用饱和水溶液法，利
用正交L₉( 3) ⁴ 对木香挥发油进行β－CD 包合。用HPLC 法测定木香挥发油及其包合物中六个化学成分的含
量。结果: 木香挥发油六个组分在不同包合条件下转移率存在明显差异。结论: 木香挥发油原化学组分比例在
β－CD 包合物中遭到了不同程度的破坏。

Objective: To observe the six chemical components in volatile oil of Aucklandia lappa
and their transfer rates in β－cyclodextrin inclusion compound． Methods: The inclusion complex were
prepared by saturated solution method，The preparation technique for volatile oil β－cyclodextrin inclusion
compound of Aucklandia lappa were investigated by using L₉( 3) ⁴ orthogonal design． the relative
content of six chemical components in volatile oil and its inclusion compounds were detected by HPLC．
Results: In different conditions， the six chemical components have a obvious difference transfer rates in
inclusion compound． Conclusion: The chemical component proportion were destroyed by different degrees
in volatile oil β－cyclodextrin inclusion compound．

R944． 5

 收稿日期: 2013－11－16; 修回日期: 2014－01－12
基金项目: 内蒙古自然科学基金( 2013MS1208)
作者简介: 孟根达来( 1964－) ，男，内蒙古医科大学附属医院药剂部副主任药师。