目的: 对分化型甲状腺癌( differentiated thyroid carcinoma，DTC) 病人采用放射性碘( ¹³¹ I) 治疗，从而
评价¹³¹ I 治疗DTC 的疗效。方法: 收集2007 ～ 2013a 在内蒙古医科大学附属医院经病理确诊的DTC 病人50 例，
男性19 例，女性31 例，年龄24 ～ 77 岁，平均51． 28±15． 43 岁。其中，PTC 28 例，FTC 22 例。术后单纯发现颈部
转移23 例，肺转移3 例，骨转移2 例。结果: PTC 组痊愈率75． 0%，好转率14． 3%，无效率7． 1%，死亡率3． 6%;
FTC 组痊愈率59． 1%，好转率27． 3%，无效率9． 1%，死亡率4． 5%。经统计学分析，χ² = 23． 93，P＜0． 001，差异
有统计学意义。术后单纯发现颈部转移23 例，肺转移3 例，骨转移2 例，经统计学分析，χ² = 18． 36，P＜0． 001，差
异有统计学意义。结论: ¹³¹ I 治疗DTC 有较好的疗效，且PTC 组治疗痊愈率高于FTC 组，¹³¹ I 治疗疗效与转移灶
部位有关，颈部转移灶治疗效果好于肺转移及骨转移。

Objective: To evaluate the effect of radioiodine treatment of differentiated thyroid carcinoma(
DTC) ． Methods: We collected the 50 patients with DTC by pathology at the Affiliated Hospital
of Inner Mongolia Medical University from 2007 to 2013． Patients were ranging in age from 24 to 77
years( mean 51． 28±15． 34) ，men 19，women 31． There were 28 cases of PTC， 22 cases of FTC． There
were neck metastasis in 23 cases， lung metastasis in 3 cases，and bone metastasis in 2 cases． Results:
The recovery rate in PTC group was 75． 0%， the remission rate 14． 3%， the inefficiency rate 7． 1%，
and the mortality rate 3． 6%． The recovery rate in FTC group was 59． 1%， the remission rate 27． 3%，
the inefficiency rate 9． 1%， and the mortality rate 4． 5%． By statistical analysis， χ²
= 23． 93，P＜0． 001， the difference was statistically significant． There was also statistically significant in
neck metastasis， lung metastasis and bone metastasis． Conclusions: Radioiodine treatment for DTC had
a good effect． The treatment of PTC is the better than FTC． The therapeutic effect was related to the metastasis．
The therapeutic effect of cervical metastasis was better than that of lung and osseous
metastasis，and lung metastasis was better than osseous metastasis．

R736． 1

 收稿日期: 2014－04－21; 修回日期: 2014－06－23
基金项目: 国家自然科学基金( 81260224) ; 内蒙古自治区科技计划项目( KJT10JH)
作者简介: 王春梅( 1982－) ，女，内蒙古医科大学附属医院核医学科医师。
通讯作者: 王雪梅，主任医师，教授，E－mail: wangxuemei201010@163． com 内蒙古医科大学附属医院核医学科， 010050