[关键词]
[摘要]
目的: 应用首次通过法肺灌注显像( First-pass radionuclide pulmonary perfusion imaging,FPPPI) 对急
性肺栓塞( Acute pulmonary embolism APE) 合并肺动脉高压( Pulmonary hypertension,PH) 的评价。方法: 20 例健
康自愿者,男12 例,女8 例,平均年龄为48. 47±13. 47 岁( 21 ~ 71 岁) ,20 例( 2007-10 ~ 2009-02) 临床诊断为急
性肺栓塞病人,男11 例,9 例,平均年龄为49. 95±16. 13 岁( 23 ~ 82 岁) ,所有受试者均行FPPPI 检查,按FPPPI
计算肺平衡时间( Lung equilibrium time LET) 。结果: FPPPI 法测定的肺平衡时间( LET) ,正常组LET 12. 18
±3. 28 sec,APE 组LET 32. 90±14. 29 sec 两组进行t 检验,t = 6. 32,P<0. 01,有统计学差别。结论: FPPPI 是评价
急性肺栓塞合并肺动脉高压的可靠、简便、无创性的方法
[Key word]
[Abstract]
Objective: The purpose of this study was to evaluate pulmonary hypertension( PH) and
stratification of risk by first-pass radionuclide pulmonary perfusion imaging( FPPPI) in patients with
PH of acute pulmonary embolism( APE) . Methods: twenty healthy volunteers( 12 males,8 females,average
age of 48. 47±13. 47) Twenty patients( 11 males,9 females,average age of 49. 95±16. 13,accumulated
from 2007-10 ~ 2009-02) with acute pulmonary embolism were included in our study. FPPPI
were performed in all Subjects. Calculated by FPPPI lung equilibration time( LET) . Results: LET by
FPPPI in healthy volunteers and APE patients were 12. 18±3. 28 sec and 32. 90±14. 29 sec, respec-
tively. It is the significance between healthy volunteers and APE patients ( P <0. 01 ) . Conclusion:
FPPPI was a reliable,convenient andnon - invasivemethod in evaluating pulmonary hypertension in
acute pulmonary embolism.
[中图分类号]
R563. 5
[基金项目]
收稿日期: 2014-06-12; 修回日期: 2014-08-14
基金项目: 国家自然科学基金项目( 81260224)
作者简介: 王静( 1980-) ,女,内蒙古医科大学附属医院职业康复科主治医师,医学硕士。
通讯作者: 王雪梅,主任医师,教授,博士生导师,E-mail: wangxuemei201010@ 163. com 内蒙古医科大学附属医院核医
学科, 010050