[关键词]
[摘要]
目的: 探讨血清同型半胱氨酸( Hcy) 与心脑血管疾病的关系。方法: 测定152 例冠心病病人,82 例
脑卒中病人和105 例健康对照组血清同型半胱氨酸( Hcy) 水平。结果: 冠心病组和脑卒中组血清同型半胱氨酸
( Hcy) 水平分别为( 21. 35±9. 78) μmol /L 和( 24. 12±11. 21) μmol /L,均明显高于健康对照组血清同型半胱氨酸
( Hcy) 水平( 10. 23±6. 83) μmol /L,比较差异有统计学意义( P<0. 01) 。结论: 血清同型半胱氨酸( Hcy) 与心脑血
管疾病病人有密切关系,高浓度的血清同型半胱氨酸( Hcy) 是心脑血管疾病病人的独立的危险因子,降低同型
半胱氨酸( Hcy) 可以预防和减少动脉粥样硬化的发生,值得进一步研究。
[Key word]
[Abstract]
Objective: To investigate the relationship between serum homocysteine( Hcy) and cardiovascular
and cerebrovascular diseases. Methods: The serum Hcy levels were detected in 152 patients
with coronary heart disease( CHD) , 82 patients with stroke and 105 healthy controls. Results: The average
level of Hcy in the patients with CHD, stroke and healthy controls was( 21. 35 ±9. 78) μmol /L、
( 24. 12±11. 21) μmol /L and( 10. 23 ±6. 83) μmol /L, respectively,Hcy level in patients with CHD,
stroke was significantly higher than that of the normal control group( P<0. 01) . Conclusion: Serum Hcy
is closely associated with cardiovascular and cerebrovascular diseases,high level Hcy is an independent
risk factor of cardiovascular and cerebrovascular diseases, lowering homocysteine level can prevent and
reduce the occurrence of atherosclerosis.
[中图分类号]
R541. 2
[基金项目]
收稿日期: 2014-06-15; 修回日期: 2014-08-16
基金项目: 国家自然科学基金项目( 81360109)
作者简介: 樊淑珍( 1963-) ,女,内蒙古医科大学附属医院检验科副主任检验师。