[关键词]
[摘要]
目的: 探究胎儿颈项透明层厚度超声( NT) 检测联合孕中期四维彩超诊断胎儿畸形的应用价值。方
法: 入选我院2013 － 01 ～ 2015 － 12 产检孕妇1230 例，予以产前胎儿颈项透明层厚度超声( NT) 检测联合孕中期
四维彩超监测与检查，对检查结果进行分析并随访至产后。结果: 孕11 ～ 14wk 1230 例妊娠产检者中，确诊异常
胎儿47 例( 3． 8%) ，NT 检测出异常胎儿45 例( 3． 7%) ，诊断准确率95． 7%，包括淋巴管囊瘤12 例( 胎儿颈项透
明层厚度增厚) ，胎死宫内20 例，胎儿异常发育13 例; 继续妊娠的1230 例孕妇孕22 ～ 28wk 四维彩超检测中，确
诊异常胎儿50 例( 4． 1%) ，四维彩超检测出异常胎儿50 例( 4． 1%) ，诊断准确率100． 0%。结论: 孕11 ～ 14wk 进
行胎儿颈项透明层厚度超声检测有助于评估胎儿唐氏综合征的风险，孕22 ～ 28wk 进行四维彩超监测有助于发
现胎儿结构异常，二者联合检测，对筛查胎儿先天畸形具有重要的临床意义。
[Key word]
[Abstract]
Objective: To evaluate the application value of fetal nuchal translucency( NT) obtained
in first trimester combined with four － dimensional ( 4D) ultrasound applied in second trimester in detecting
fetal deformities． Methods: A total of 1230 fetuses were selected which accepted NT inspection
and 4D ultrasound systematic examing between January 2013 and December 2015 in our department．
The detecting results were analyzed and followed up to the fetus after birth． Results: During 11 ～ 14
weeks gestation，47 ( 3． 8%) out of 1230 fetues were diagnosed confirmedly with deformities，with 45
( 3． 7%) fetus( 12 cases had neck lymphatic hygroma， 20 cases with intrwith abnormal development) were discovered by NT inspection， so the diagnostic accuracy was 95． 7%;During 22 ～ 28 weeks gestation， the 1230 cases were given 4D ultrasound systematic examination，50
( 4． 1%) fetuses were diagnosed confirmedly with deformities，all of which were detected by 4D ultrasound，
so the diagnostic accuracy was 100． 0%。Conclusion: Fetal NT inspection helps to assess the
risk of fetal down syndrome in 11 ～ 14 weeks gestation，and the 4D ultrasound systematic examination
can help find fetal structural abnormalities． The combination of fetal NT inspection and 4D ultrasound
has important clinical significance for screening fetal congenital anomalies．auterine fetal death，13 cases
[中图分类号]
R445． 1
[基金项目]
收稿日期: 2015 － 12 － 04; 修回日期: 2016 － 02 － 24
基金项目: 内蒙古医科大学附属医院( NYFY YB2014002) ; 内蒙古自然科学基金( KJT 15 MS8123)
作者简介: 福林( 1975 － ) ，男，内蒙古医科大学附属医院超声诊断科副主任医师。
通讯作者: 张小杉，主任医师，E － mail:
13947133133@163． com 内蒙古医科大学附属医院超声诊断科， 010050
