[关键词]
[摘要]
目的: 探讨血浆超敏肌钙蛋白T( hs - cTnT) 的定量与急性冠状动脉综合征( ACS) 的相关性联系。
方法: 选取2014 - 08 ~ 2015 - 08 我院收治的急性冠状动脉综合征病人157 例和在我院进行检查的健康对照组
72 例。将其分为三组: 实验组( 急性冠状动脉综合征组) 又分为不稳定型心绞痛( UA) 组和急性心肌梗死( AMI)
组及对照组( 正常组) 。监测病人和正常人的血浆hs - cTnT 值变化情况,同时将急性冠状动脉综合征病人的血
浆hs - cTnT 水平和正常人机体内的血浆hs - cTnT 做对比研究。结果: 急性冠状动脉综合征病人的( UA) 组血
浆hs - cTnT 含量为( 0. 45 ± 0. 16) ng /mL、( AMI) 组血浆hs - cTnT 含量为( 0. 91 ± 0. 32) ng /mL 明显高于正常组
血浆hs - cTnT( 0. 032 ± 0. 01) ng /mL,UA 组与AMI 组比较差异有统计学意义( P < 0. 05) ; 病人组与对照组比较
有显著统计学意义( P < 0. 01) 。另为血浆hs - cTnT 在不稳定型心绞痛( UA) 组和急性心肌梗死( AMI) 组病人
中阳性率分别为86. 3%、100%,二者血浆hs - cTnT 水平比较,差异无统计学意义( P > 0. 05) ,正常对照组阳性率
为0%。结论: 定量检测血浆hs - cTnT 含量能够有效的反应病人的急性冠状动脉综合征病变,对该病的诊治和
预后判断具有非常重要的应用价值,二者之间具有相关性联系。
[Key word]
[Abstract]
Objective: To discuss the correlation of quantitative high - sensitivity troponin T( hs -
cTnT) and acute coronary syndrome( ACS) . Methods: 157 acute coronary patients were selected in our
hospital from August 2014 to August 2015,while 72 healthy controls were examined. They will be divided
into three groups: the experimental group( acute coronary syndrome group) which was divided into
unstable angina( UA) and acute myocardial infarction( AMI) group, the third group was control group
( control group) . Detecting the hs - cTnT in patients and healthy groups,and the levels of hs - cTnT
were compared between the experimental group and the control group. Results: The result of hs - cTnT
in UA group was( 0. 45 ± 0. 16) ng /mL,The result of hs - cTnT in AMI group was
( 0. 91 ± 0. 32) ng /mL. The values were significantly higher than the control group( 0. 032 ± 0. 01) ng /mL. UA and AMI
had statistically difference( P < 0. 05) ; The experimental group and the control group had statistically
significance( P < 0. 01) . The positive rate of hs - cTnT in UAgroup and AMI group were 86. 3% and
100%respectively,and the difference had no statistically significance( P > 0. 05) . The positive rate in
control group was 0%. Conclusion: Quantitative detection of hs - cTnT can be an effective response in
patients with acute coronary syndrome disease,and there is correlation between the hs - cTnT and the
disease.
[中图分类号]
R543. 3
[基金项目]
收稿日期: 2016 - 01 - 03; 修回日期: 2016 - 04 - 07
基金项目: 内蒙古自治区自然基金( 2014MS0854)
作者简介: 樊淑珍( 1963 - ) ,女,内蒙古医科大学附属医院检验科主任检验师。