目的: 本文将采用micro－CT 技术对人颈椎寰枢椎骨的显微结构作研究分析。方法: 采用micro－CT
技术，选择不同的扫描协议，对同一样本人体颈椎寰枢椎骨进行研究，分析不同协议下骨骼的扫描结果，选择最
优的扫描协议，分析人体骨骼的骨小梁等显微结构的信息。结果: Micro－CT 扫描结果显示，在Bin1＆High 扫描协
议下采集的图像，能够清楚的看到颈椎寰枢椎骨内骨小梁的显微结构，并且可以得到骨体积/全体积、骨表面积/
骨体积、骨小梁厚度、骨小梁数目、骨小梁间隙、骨小梁模式因子和皮质壁厚等参数信息。结论: Micro－CT 是研
究骨小梁的显微结构变化，骨密度变化，骨松质和骨皮质的变化等领域中的一种重要技术。

Objective: Micro－CT is a non－destructive three－dimensional imaging technology．The
microstructure of the sample can be clearly seen without destroying the sample．In this paper， the microstructure
of human cervical atlantoaxial vertebrae will be studied and analyzed through micro－CT technology．
Methods: The same human atlantoaxial vertebrae were studied with micro－CT by selecting different
scan protocols，and analyzing the scan results under different protocols．The trabecular bone of the
sample and other microstructure information were analyzed through the scan result under the optimal
scan protocol．Results: Micro－CT imaging showed that the microstructure of human cervical atlantoaxial
vertebrae could be seen clearly under the Bin1＆High scan protocol，and other microstructure information，
such as bone volume /total volume，bone surface area /bone volume， trabecular thickness，number
of trabeculae， trabecular space， trabecular pattern factor and cortical wall thickness and so on，could be
obtained．Conclusion: Micro－CT is an important technique in studying the microstructural changes of
trabecula， the changes of bone density， the changes of cancellous bone and cortical bone．

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 收稿日期: 2016－08－09; 修回日期: 2016－09－23
基金项目: 国家自然科学基金项目( 81360227) ; 内蒙古自治区自然科学基金项目( 2015BS( LH) 0803)
作者简介: 李剑波( 1983－) ，男，内蒙古医科大学附属医院核医学科助理研究员，医学博士。