目的: 比较DWI 的ADC 值及IVIM 的ADCstand，D，D* ，f 值在诊断前列腺癌、腺体型前列腺增生、
基质型前列腺增生的价值。方法: 回顾性分析经穿刺证实的前列腺癌病灶30 例、腺体型前列腺增生病灶15 例、
基质型前列腺增生病灶26 例的临床资料。所有病人均行小FOV T2WI、T1WI、DWI、多b 值DWI 及动态增强
DCE 检查。根据病理结果将DWI 及IVIM 图像进行匹配，测定各病理类型的ADC，ADCstand，D，D* ，f 值，采用
方差分析和秩和检验进行差异性比较。受试者( ROC) 曲线分析各参数鉴别诊断效能。结果: ADC、ADCstand、D、
D* 值在鉴别前列腺癌、腺体型增生、基质型增生中均有统计学意义，f 值无统计学意义。在诊断前列腺癌时
ADC，ADCstand，D 均有较高诊断较能，在诊断前列腺癌及基质型增生曲线下面积( AUC) 最大均为D 值。结论:
ADC，ADCstand，D，D* 值在鉴别前列腺癌、腺体型增生、基质型均有价值。IVIM 的D 值在诊断前列腺癌和基质
型增生时具有最佳诊断效能。

Objective: To compare the diagnosis values of the ADC that calculated from diffusionweighted
imaging( DWI) and the ADCstand，D，D* ，f value derived from IVIM for prostate cancer
( PC) ，glandular prostate hyperplasia ( GH) and stromal prostate hyperplasia ( SH) ． Methods: The
clinical data of 30 cases with PC，15 cases with GH and 26 cases with SH，who were proven by ultrasound
guided biopsy were retrospectively analyzed． All the patients underwent MRI examination
including T2WI，T1WI，DWI， IVIM and DCE before biopsy．The match of target biopsy area and DWI
and IVIM images was done based on the pathology results．Then the ADC，ADCstand，D，D* ，f values
were measured．Variance analysis and Rank sum test were used for difference comparison，and receiver
operating characteristic(ROC) analysis was performed to evaluate their diagnostic efficiency．Results:
There were significant differences in ADCstand，ADC，D，D* values among different groups，The D has
the largest AUC in the PC and SH．Conclusion: ADC，ADCstand，D，D* value in the diagnosis of PC，
GH and SH have diagnostic value．The D that calculated from IVIM has the best diagnostic efficacy for
PC and SH．

R815

 收稿日期: 2016－12－08; 修回日期: 2017－02－20
基金项目: 内蒙古医科大学科技百万项目( YKD2016KJBW( LH) 004)
作者简介: 吴慧( 1980－) ，女，蒙古族，内蒙古医科大学附属医院影像诊断科副主任医师。
通讯作者: 任建军，主任医师E－mail: renjj．ok@ 163．com 内蒙古医科大学附属医院， 010050