[关键词]
[摘要]
目的:探讨急性脑梗死病人血浆同型半胱氨酸、超敏C 反应蛋白、D－二聚体、脂蛋白a 水平的改变
及临床意义。方法:选自我院于2015－06～ 2016－06 期间收治的急性脑梗死病人84 例，同期选自我院于2015－06
～ 2016－06 期间的健康体检者60 例作为对照组。检测血浆同型半胱氨酸、超敏C 反应蛋白、D－二聚体、脂蛋白a
含量。结果:观察组血浆同型半胱氨酸、超敏C 反应蛋白、D－二聚体及脂蛋白a 含量明显高于对照组，均有统计
学差异( P＜0．05) ;观察组同型半胱氨酸、超敏C 反应蛋白、D－二聚体及脂蛋白a 阳性率高于对照组，均有统计学
差异( P＜0．05) ;大面积梗死组血浆同型半胱氨酸、超敏C 反应蛋白、D－二聚体及脂蛋白a 含量高于中面积梗死
组和小面积梗死组，中面积梗死组血清同型半胱氨酸、超敏C 反应蛋白、D－二聚体及脂蛋白a 含量高于小面积
梗死组，均有统计学差异( P＜0．05) 。结论:血浆同型半胱氨酸、超敏C 反应蛋白、D－二聚体、脂蛋白a 水平与急
性脑梗死病情发生、发展密切相关。
[Key word]
[Abstract]
Objective:To investigate the changes and clinical significance of plasma homocysteine，
high－sensitivity C reactive protein(hs－CRP)，D－D dimer and a in patients with acute cerebral infarction．
Methods:84 patients with acute cerebral infarction admitted in our hospital from June 2015 to
2016 in were selected from the same period in our hospital in the period of 2016 in the year of June in
June 2015 as the control group．Detection of plasma homocysteine，high sensitive C reactive protein，DD
polymer，lipoprotein a content．Results:the observation group of plasma homocysteine and high－sensitivity
C reactive protein，two D－D dimer and apolipoprotein A were significantly higher than the control
group ( P ＜ 0．05 ); homocysteine and high － sensitivity C reactive protein，two D － dimer and
lipoprotein a were higher than that of control group ( P ＜ 0．0 5 ); large area infarction group
homocysteine，high sensitive C reactive protein，two D－D dimer and lipoprotein a were higher than in
the area of infarction group and small infarct group，in the area of infarction group serum homocysteine
and high－sensitivity C reactive protein，two D－D dimer and lipoprotein a content higher than the small
area infarction group were statistically significant(P＜0．05)．Conclusion:the levels of plasma homocysteine，
high－sensitivity C reactive protein，D－D dimer and a are closely related to the occurrence and
development of acute cerebral infarction．
[中图分类号]
R 322．81
[基金项目]
收稿日期: 2017－02－11;修回日期: 2017－04－02
基金项目: 内蒙古自治区社会发展基金(2015)
作者简介: 许琳(1978－)，女，内蒙古医科大学附属医院检验师。
通讯作者: 杜肖彦，副主任检验师，硕士研究生导师，E－mail:1271230526@ qq．com 内蒙古医科大学附属医院，010050
