目的:探讨C－反应蛋白、白介素6 及降钙素原三者联合检测在感染性疾病中的诊断价值。方法: 选
取2015－01～ 2015－08 期间入住我院ICU 的感染性疾病病人106 例，将其分为细菌感染组59 例及病毒感染组47
例作为实验组，并将在我院进行检查的健康体检者45 例作为对照组。监测病人和正常人的血清中C－反应蛋
白、白介素6 及降钙素原值的变化情况与阳性率，同时将感染性疾病病人的血清中C－反应蛋白、白介素6 及降
钙素原水平与正常人机体内的血清中C－反应蛋白、白介素6 及降钙素原做对比研究。结果: 细菌感染组病人
CRP、IL－6 和PCT 含量分别是( 146．3±19．87) mg /L、( 99．6±22．6) pg /mL 和( 6．32±1．69) ng /mL，明显比病毒感染
组、健康对照组高，病毒感染组病人的CRP、IL－6 和PCT 含量比健康对照组高，三组间比较差异具有统计学意义
( P＜0．05) 。细菌感染组血清CRP、IL－6 与PCT 阳性率分别是52．5%、59．3%、89．8%，明显比病毒感染组和健康对
照组高，差异有统计学意义( P＜0．05) 。结论: 血清中CRP、IL－6 和PCT 的含量均是感染性疾病诊断的可靠指
标，也能分辨感染类型，并对病人的诊断治疗以及预后的评估有着非常重要的指导意义。

Objective:To investigate the value of C－reactive protein(CRP)combining interleukin－
6(IL－6)with procalcitonin(PCT)in the diagnosis of infectious diseases．Methods:106 patients who are
admitted to ICU with infectious diseases in Affiliated Hospital of Inner Mongolia Medical University
from January 2015 to August 2015 were divided into two groups，one was bacterial infection with 59 patients
and the other was viral infection with 47，which both considered to be experimental group．Besides
there are 45 patients who have a physical examination in our hospital regarding as the control group．
Monitorring the dynamic change and positive rate of CRP，IL－6 and PCT in serum．And then making
comparition of the experimental group and control group on the indicators of CRP，IL－6 and PCT in the
serum．Results:The average concentration of CRP，IL－6 and PCT of patients with bacterial infection respectively
were(146．3±19．87)mg /L，(99．6±22．6)pg /mL and(6．32±1．69)ng /mL，which were signifi-
cantly higher than these who were viral infection and healthy．The group of viral infection was significantly
higher than the healthy control group．There was significant difference between the three groups
(P＜ 0．05)． The positive rates of CRP，IL － 6 and PCT respectively were 52．5%，59．3%and 89．8%，
which were significantly higher than who were viral infection and healthy(P＜0．05)．Conclusion:The
indicators of CRP，IL－6 and PCT are reliable of diagnosing infectious diseases，and are helpful to distinguish
the type of infection．Furthermore，these indicators have important value for the treatment and
prognosis of patients which can guide the doctors．

R 446．6

 收稿日期: 2017－01－18;修回日期: 2017－03－18
基金项目: 内蒙古自治区自然科学基金(2014MS0854)
作者简介: 樊淑珍(1963－)，女，内蒙古医科大学附属医院检验科主任检验师。