目的: 探讨依达拉奉注射液对急性脑梗死病人神经功能的影响。方法: 按照入院顺序抽签随机将
2013－05～ 2015－05 来我院接受治疗的84 例急性脑梗死病人纳入本研究，并分为实验组42 例与对照组42 例。
对照组以阿司匹林肠溶缓释片治疗，实验组在此基础上加用依达拉奉注射液治疗。观察2 组治疗效果。结果:
实验组病人治疗效果优于对照组( P＜0．05) ; 2 组病人治疗前后凝血活酶时间、活化部分凝血活酶时间、凝血酶时
间、血浆纤维蛋白原指标均无明显变化( P＞0．05) ; 治疗后，2 组NIHSS 评分均明显降低，BI 评分均明显升高( P＜
0．05) ，且实验组NIHSS 评分低于对照组，BI 评分高于对照组( P＜0．05) ; 2 组病人治疗期间不良反应发生率相似
( P＞0．05) 。结论: 急性脑梗死病人依达拉奉注射液可以有效提高活动能力，减少神经损伤，且未对凝血功能造
成影响，疗效肯定。

Objective: Discussion edaravone injection on nerve function in patients with acute cerebral
infarction．Methods: In accordance with the order of admission lottery randomly 2013－05 ～ 2015－
05 to our hospital treated 84 cases of acute cerebral infarction patients included in this study， 42 cases
were divided into experimental group and the control group of 42 patients． The control group in the
treatment of Aspirin EnteriC－coated SustainedRelease Tablets， the experimental group was based on
the use of edaravone injection．Two groups were observed therapeutic effect．Results: The patient outcomes
than the control group ( P ＜ 0．05 ) ; two groups of patients before and after treatment
thromboplastin time，activated partial thromboplastin time， thrombin time， fibrinogen index did not
change significantly( P＞0．05) ; after treatment， the two groups were significantly lower NIHSS score，BI
score were significantly increased( P＜0．05) ，and the experimental group than the control group NIHSS
score，BI score was higher( P＜0．05) ; 2 patients incidence of adverse reactions similar( P＞0．05) during
treatment．Conclusion: Patients with acute cerebral infarction edaravone injection can improve mobility，
reduce nerve damage，and did not affect blood coagulation，more effective．

R965

 收稿日期: 2017－02－22; 修回日期: 2017－06－03
基金项目: 国家自然科学基金( 81360213)
作者简介: 贾媛媛( 1982－) ，女，陕西省宝鸡市中医院主治医师。
通讯作者: 吴荷花，主任技师，E－mail: hehua@ live．ca 内蒙古医科大学附属医院， 010050