目的: 探讨224 例蒙古族与汉族原发性高血压( essential hypertension，EH) 血压变异性及靶器官损害
的特点。方法: 选择2014－05～ 2016－12 收住内蒙古医科大学附属医院老年病科高血压病人224 例，分为汉族
118 例，蒙古族106 例。收集两组病人一般资料并测得其24 h 动态血压( ABPM) 各参数进行比较，同时行彩色多
普勒超声检测颈动脉内膜厚度( IMT) 及左室肥厚( LVH) 并进行对比。结果: ( 1) 蒙古族组饮酒率、体重指数
( BMI) 、甘油三酯( TG) 、低密度脂蛋白( LDL－C) 明显高于汉族组差异均有统计学意义( P＜0．05或P＜0．01) 。( 2)
蒙古族各组EH 病人24 h 收缩压标准差( 24 hSSD) 、日间收缩压标准差( dSSD) 、夜间收缩压标准差( nSSD、夜间
舒张压标准差( nDSD) 、3 级组24 h 舒张压标准差( 24 hDSD) 均显著组显著高于汉族组，差异具有统计学意义( P
＜0．05或P＜0．01) 。蒙古族1、2 级组24 h 舒张压标准差( 24 hDSD) 及各组日间舒张压标准差( dDSD) 高于汉族
组，但差异无统计学意义( P＞0．05) 。( 3) 蒙古族组1、2 级和3 级组非勺型率、左室肥厚率、颈动脉内膜斑块、狭
窄率均显著高于对应汉族组，差异均有统计学意义( P＜0．01或P＜0．05) 。结论: 蒙古族EH 病人24 h 各时间段收
缩压变异性和夜间舒张压变异性明显高于汉族病人，心脏、颈动脉损害率亦明显高于汉族EH 病人。

Objective: To study characteristics of blood pressure variability and target organ damage
in 224 cases Han and Mongolian nationality patients with essential hypertension( EH) ．Methods: From
May 2014 to December 2016， 224 patients with( EH) were collected in Gerontology Department of the
Affiliated Hospital of Inner Mongolia Medical University．The patients were divided into Han nationality
group( n = 118) and Mongolian nationality group( n = 106) ．Common datas and 24－hours dynamic parameters
of ambulatory blood pressure Monitoring( ABPM) were analyzed in all subjects． Echocardiography
were used to determin carotid artery intimadia thickness( IMT) and left ventricular hypertrophy
( LVH) ，which were compared in two group，meanwhile．Results:( 1) Drinking，body mass index( BMI) ，
triglyceride( TG) ，low density Lipoprotein cholesterol( LDL－C) were significantly higher in Mongolian
nationality group than in Han nationality group( P＜0．01or P＜ 0．05) ． ( 2) The levels of 24 hSSD、24
hDSD、dSSD、nSSD、nDSD in Mongolian nationality group were significantly higher than those in Han
nationality group( P＜0．05or P＜0．01) ．The differences were statistically significant( P＜0．05or P＜0．01) ．
The dSSD of Mongolian nationality group were higher than that of Han nationality group， the difference
were not statistically significant．( 3) Nondipper ratio， the incidence of LVH，carotid artery plaque and
stenosis were significantly higher in Mongolian nationality group than in Han nationality group( P＜0．01
or P＜0．05) ．There were significant differences between the two groups．Conclusion: Systolic pressure
variability of the short time period and diastolic pressure variability of night in Mongolian nationality patients
with EH are higher than in Han nationality patients．Meanwhile the incidence of the impairment
with heart and carotid artery in Mongolian nationality patients are also higher than in Han nationality
patients．

R544．1

 收稿日期: 2017－03－11; 修回日期: 2017－08－23
基金项目: 内蒙古自治区卫生和计划生育委员会医疗卫生科研计划项目( 201302074)
作者简介: 郝永哲( 1981－) ，女，内蒙古医科大学附属医院老年病科主治医师，医学硕士。
通讯作者: 程文俊，主任医师，硕士研究生导师，E－mail chengwenjun_nyfy@ 163．com 内蒙古医科大学附属医院老年病
科， 010050