[关键词]
[摘要]
目的: 观察含20%小牛血去蛋白提取物眼用凝胶治疗机械性损伤角膜上皮的临床效果。方法: 选取
机械性损伤致角膜上皮缺损的病人120 例,220 眼,随机分为观察组用小牛血去蛋白提取物眼用凝胶60 眼,对照
组使用0.3%氧氟沙星滴眼液,两组均滴眼4 次/d,用药后第3 d,第7 d 观察两组病人眼部症状反应及角膜上皮
愈合情况。结果: 含20%小牛血去蛋白提取物眼用凝胶组治疗机械性角膜上皮缺损第3 d、第7 d 有效率
78.33%、93.33%。0.3%氧氟沙星滴眼液治疗机械性角膜上皮缺损第3 d、第7 d 有效率55.00%、71.67%。两者有
效率比较差异有统计意义( P<0.05) 。结论: 含20%小牛血去蛋白提取物眼用凝胶在短时间内对角膜上皮愈合
有显著促进作用,值得在临床上广泛应用。
[Key word]
[Abstract]
Objective: To observe the clinical effect of 20%calf serum deproteinized ophthalmic gel
in the treatment of corneal epithelium injury.Methods: 120 cases of corneal epithelial defect caused by
mechanical injury were randomly divided into observation group( 60 eyes) ,eye drop group( 60 eyes)
and control group( 0.3%ofloxacin eye drops) .The two groups of eye drops 4 times /min,3 days,7 days
after treatment to observe the two groups of patients with eye symptoms and corneal epithelial healing.
Results: The effective rates of 78.33%and 93.33%on the third day and seventh day of mechanical corneal
epithelial defect treated with 20%calf serum deproteinized ophthalmic gel group.0.3%ofloxacin eye
drops in the treatment of mechanical corneal epithelial defect 3 days,7 days efficiency 55.00%、
71.67%, the difference have statistics meaning( P<0.05) .Conclusion: The ophthalmic gel containing
20%fetal calf serum deproteinized extract can promote the healing of corneal epithelium in a short time.
It is worthy to be widely used in clinic.
[中图分类号]
R77
[基金项目]