目的: 通过了解重症监护病房( ICU) 中鲍曼不动杆菌感染的分布特征以及鲍曼不动杆菌的耐药状
况，为临床的防治以及抗菌药物的正确使用提供参考依据。方法: 收集我院重症监护病房( ICU) 1762 例病人病
例资料，选择病人的痰、中断尿、分泌物、中心静脉导管等部位标本的细菌培养结果，对培养分离到的鲍曼不动杆
菌的分布和细菌耐药的状况进行了分析。结果: 1762 例病人中检出感染菌892 株，其中鲍曼不动杆菌129 株; 自
2014～ 2016 鲍曼不动杆菌在ICU 的检出率呈逐年上升趋势，由11．68%上升至16．31%; 129 株鲍曼不动杆菌主要
分布在下呼吸道，约81．40%; 药敏结果是对多种抗菌药物耐药，并且耐药率也是逐年上升，对丁胺卡那霉素耐药
率最低。结论: ICU 病房的鲍曼不动杆菌检出率呈现逐年上升，耐药情况比较严重，需要加强监测和积极干预，
合理使用抗菌药物，医护人员要严格遵守无菌操作，减少鲍曼不动杆菌感染以及交叉感染发生。

Objective: By investigating the distribution characteristics and drug resistance of Acinetobacter
baumannii in intensive care unit ( ICU) ， it provides a reference for clinical prevention and
treatment， furthermore， for proper use of antimicrobial agents． Methods: The clinical data of 1762
patients were collected in our hospital ICU．We collected the bacterial culture results of sputum，middle
urine，secretions and central venous catheters and analyzed distribution and bacterial resistance．
Ｒesults: Among the 1762 cases， 892 cases of patients infected with bacteria were detected，where 129
cases are Acinetobacter baumannii; The 129 strains of Acinetobacter baumannii are mainly distributed
in the lower respiratory tract，accounting for about 81．40%and the detection rate of Acinetobacter baumannii
in ICU increased from 11．68%to 16．31%from 2014 to 2016．The drug susceptibility results were
that they were resistant to a variety of antibiotics，and the drug resistance rate is also increased year by
year．Besides， the resistance to amikacin is the lowest．Conclusion: The detection rate of Acinetobacter
baumannii in ICU is increasing year by year，and the drug resistance is much more serious．It is necessary
to strengthen the monitoring and active intervention and the rational use of antibiotics．The doctor
and nurse should comply with the aseptic operation strictly and reduce Acinetobacter baumannii Infection
and cross－infection．

Ｒ378

 收稿日期: 2018－01－07; 修回日期: 2018－03－06
基金项目: 内蒙古自治区自然基金立项资助课题( 2013MS11113)
作者简介: 燕成岭( 1962－) ，男，内蒙古自治区人民医院检验科主任检验师。
通讯作者: 樊淑珍，主任检验师，E－mail: nmyyycl@ 126．com 内蒙古医科大学附属医院检验科， 010050