[关键词]
[摘要]
目的: 研究蒙药复方述达格-4 对小鼠抗炎镇痛的作用。方法: 采用肉芽肿实验法、涂二甲苯至小鼠
耳廓使耳朵肿胀法观察抗炎作用,采用腹腔注射醋酸致小鼠扭体法观察镇痛作用。结果: 各剂量组与模型组比
较,得出蒙药复方述达格-4( 150 mg /kg) 组能抑制棉球致小鼠肉芽肿的生长,肉芽肿的重量为16.8±0.77mg; 抑制
二甲苯致小鼠耳肿胀,抑制率26.23%; 抑制冰醋酸引起的小鼠扭体反应,抑制率31.45%。结论: 蒙药复方述达格
-4 对小鼠有显著的抗炎镇痛作用。
[Key word]
[Abstract]
Objective: To study the anti-inflammatory and analgesic effects of Mongolian medicine
compound Sendeng-4 inmice.Methods: The anti-inflammatoryeffects were observed by the cotton ball
granuloma, the methods of mice ear swelling. The analgesia effects were observed by the methods of
writhing body.Results: Comparedwithmodel group,Mongolian medicine compound Sendeng-4( 150 mg /
kg) could inhibit the growth of the cotton granuloma in mice, the weight of granuloma is 16.8±0.77mg
and ear swelling induced by dimethylbenzene, inhibition ratio is 26.23%, inhibit the writhing body reaction
induced by acetic acid, inhibition ratio is 31.45%.Conclusion: Mongolian medicine compound Sendeng-
4 has anti-inflammatory and analgesic effects.
[中图分类号]
R965.1
[基金项目]
收稿日期: 2017-10-25; 修回日期: 2018-03-10
基金项目: 自治区级大学生创新创业训练计划项目( 201610132002) ; 内蒙古自治区高等学校“青年科技英才支持计划”青年
科技领军人才( NJYT-14-A12)
作者简介: 嵇增云( 1995-) ,女,内蒙古医科大学2017 级在读硕士研究生。
通讯作者: 董玉,教授,医学博士,博士生导师,E-mail: dongyu010@ 126.com 内蒙古医科大学, 010059