[关键词]
[摘要]
目的: 探究蒙药复方协日嘎－4 不同配伍组合对总生物碱、盐酸小檗碱含量的影响。方法: 以组方中
姜黄、黄柏、栀子、蒺藜的配伍为因素，配伍后处方提取液中总生物碱、盐酸小檗碱的含量为指标，分别研究不同
配伍对总生物碱、盐酸小檗碱含量的影响。结果: 通过统计分析，分别研究不同配伍组中总生物碱、盐酸小檗碱
含量之间的关系，其中全方组中总生物碱最高( P＜0．05) ，盐酸小檗碱的提取量较高( P＜0．05) 。结论: 不同的药
味组合中，总生物碱、盐酸小檗碱的溶出具有显著性差异( P＜0．05) 。
[Key word]
[Abstract]
Objective: To study the effects of the total alkaloid and berberine hydrochloride in different
drug compatibility of Mongolian medicine compound Xieriga － 4．Methods: The different drug
compatibility factors were constituted by turmeric，cork，gardenia and tribulus terrestri， the contents of
total alkaloids and berberine hydrochloride in the extract of prescription compatibility were indexes， to
study the effects of different herbs on the contents of total alkaloids and berberine hydrochloride．Ｒesults:
Through the statistical analysis of the results， the study of the relationship between Xieriga－4 in
different drug compatibility and the total alkaloid and berberine hydrochloride， the total alkaloids in the
whole drug compatibility were the highest( P＜0．05) ，and the extraction amount of berberine hydrochloride
was higher( P＜0．05) ．Conclusion: The dissolution of the total alkaloid and berberine hydrochloride
in different drug compatibility of Xieriga－4 has significant difference( P＜0．05) ．
[中图分类号]
Ｒ965
[基金项目]
收稿日期: 2018－01－10; 修回日期: 2018－05－10
基金项目: 内蒙古自治区科技计划重大项目( 2016) ; 内蒙古自治区草原英才创新团队
作者简介: 李斌鑫( 1992－) ，男，内蒙古医科大学2015 级在读硕士研究生。
通讯作者: 董玉，医学博士，教授，博士生导师，E－mail: dongyu010@ 126．com 内蒙古医科大学， 010059
