[关键词]
[摘要]
目的: 本文探讨血小板减少的病因与补体C 1 q 降低并且ANA 阳性的相关性。方法: 选择2017-05
-09~ 2017-12-31 期间的230 例来我院就诊病人,方法用固相凝集法检测血小板抗体。结果: 230 例病人中共检
出血小板抗体阳性68 例(29.6%)、弱阳性135 例(58.7%);阴性27 例(11.7%);并对其中血小板抗体阳性86 例、
弱阳性54 例与补体C 1 q 降低且ANA 阳性进行统计学分析,有显著相关性(P<0.01)。结论: 自身免疫性疾病
(AID)是引起血小板抗体阳性重要因素。血小板抗体的筛查,常用于临床的有配合型输血、早期流产发生的风
险提供诊断和治疗依据,有利于新生儿同种免疫性血小板减少性紫癜预防,对血小板抗体引起的血小板减少疾
病进行对症治疗和预防有着重要意义。
[Key word]
[Abstract]
Objective:To detect platelet antibodies( Paig) when necessary as a screening tool for
thrombocytopenia disorders.Methods:This article explores the causes of thrombocytopenia.The correlation
with the complement C1 q decreased and Ana positive.Select May 9,2017 ~ 2017 year December
31230 cases to our hospital patients,methods by solid-phase agglutination assay.Results:230 patients
with platelet antibody positive 68 cases(29.6%),weak positive 135 cases(58.7%),negative 27 cases
(11.7%);The results showed that there were significant correlations between 86 cases of platelet antibody
positive and 54 cases with C1 q and Ana Positive(P<0.01).Conclusion:Autoimmune disease
(AID)is an important factor that causes platelet antibody positive. Platelet antibody screening,often
used in clinical with the combination of blood transfusion,the risk of early miscarriage to provide diagnosis
and treatment,in favor of newborn infants with the same immune thrombocytopenic purpura prevention,
platelet antibody-induced thrombocytopenia disease for symptomatic treatment and prevention
is of great significance.
[中图分类号]
R714.21
[基金项目]