药源性胰腺炎( drug－induced pancreaoitis，DIP) 是一种特殊的消化系统类疾病，它与药物的种类存在 着密切关系。近年来，多种类药物的大量使用使得 DIP 的发病率呈现上升趋势。其临床表现与其他致病因素导 致的急性胰腺炎( Acute pancreatitis，AP) 相似，由于其没有特异性检测指标，因此在与其他类型的 AP 鉴别中比 较困难。尽管药源性胰腺炎较其他病因所致胰腺炎少见，但为了提高临床用药安全性，仍应加强对药源性胰腺 炎相关药物的监测。本文就 DIP 的好发人群、发病机制以及药物分类的研究进展做一综述。

Drug －induced pancreatitis( DIP) is a special type of digestive system disease that is closely related to the type of drug．In recent years，the large use of a variety of drugs has led to an in- creasing incidence of DIP．Its clinical manifestations are similar to acute pancreatitis( AP) caused by other pathogenic factors．Because it has no specific detection index，it is difficult to identify with other types of AP．Although pancreatitis caused by drug －induced pancreatitis is rare compared with other causes，in order to improve the safety of clinical drugs，the monitoring of drugs related to drug－induced pancreatitis should be strengthened．This article reviews the research progress of DIP，the pathogenesis and drug classification．

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收稿日期: 2018－07－27; 修回日期: 2019－03－05 基金项目: 内蒙古科技计划项目( kjjh17) 作者简介: 张娜( 1993－) ，女，内蒙古医科大学 2016 级在读硕士研究生。 通讯作者: 陈平，主任医师，硕士研究生导师 E－mail: nmgcp@ sina．com 内蒙古医科大学附属医院消化内科，010050