[关键词]
[摘要]
目的:探讨胎儿大脑中动脉(middle cerebral artery,MCA)与脐动脉(umbilical artery,UA)的阻力指标 在高血压产妇母婴结局的预测价值。方法:选取我院妇产科 147 例妊娠期高血压产妇,按疾病轻重分为轻度组 78 例,重度组 69 例,选择正常孕妇 172 例作为对照组。采取彩色多普勒超声检测胎儿 MCA 与 UA 阻力指标并 计算其S / D、PI 及 RI 比值,用各阻力指标及比值与妊娠结局作 ROC 曲线。结果:对照组与重度组 UA、MCA 阻力 指标及比值组间差异显著(P<0.05),轻度组与重度组 UA、MCA 阻力指标及比值组间差异显著(P<0.05)。三组 妊娠结局比较有显著差异(P<0.05)。经 ROC 分析妊娠结局,MCA 与 UA 阻力指标优于单一应用 MCA 或 UA。 结论:疾病恶化后胎儿 UA 阻力指标上升,MCA 及 MCA 与 UA 阻力指标下降,RIMCA/ UA 对妊娠期高血压疾病 预测价值佳。
[Key word]
[Abstract]
Objective:To investigate the predictive value of fetal MCA,resistance indexes of MCA and UA in maternal and infant outcomes of HDCP women.Methods:147 cases of HDCP women and 172 healthy pregnant women(control group)in our hospital were selected.The HDCP women were di vided into mild group(n = 78)and severe group(n = 69)according to the disease severity.The resistance indexes of MCA and UA,S / D ratio,PI/ RI were calculated through color Doppler ultrasound.Then the ROC curve was used to analyze the resistance index and ratio of MCA and UA.Results:There were sig nificant differences between the control group and the severe group in resistance index and ratio of UA and MCA(P<0.05).There were significant differences between the mild group and the severe group in resistance index and ratio of UA and MCA(P < 0.05). The pregnancy outcomes showed significant difference among three groups(P<0.05).ROC analysis showed that the diagnosis value of combined de tection was higher than that of the single detection.Conclusion:After the deterioration of the disease, fetal UA resistance index is increased,while fetal MCA as well as resistance index ratio of MCA and UA are decreased.The predictive value of RIMCA/ UA for HDCP women is good.
[中图分类号]
R714.56
[基金项目]