目的：探究拜阿司匹林与氯毗格雷联合治疗方案对120例急性非ST段抬高型心肌梗死（NSTEMI）患者的治疗作用。方法：收集NSTEMI患者120例，随机分为联合治疗组60例，对照组60例，对照组单独服用氯毗格雷；联合治疗组服用拜阿司匹林和氯毗格雷联合治疗。检测两组血清IL-1β、IL-6、TNF-α、hs-CRP水平；监测两组并比较LVESD、LVDd、LVEF、LVEDV和LVESV的改变；对两组患者进行随访观察终点指标。结果：联合治疗组与对照组血清IL-1β、IL-6、TNF-α及hs-CRP水平、心功能及并发症均优于对照组（均P < 0.05）。结论：联合应用拜阿司匹林与氯毗格雷在治疗NSTEMI患者上可发挥协同作用，值得临床推广应用。

Abstract Objective: Explore the therapeutic effect of the combination of aspirin and clopidogrel on 120 patients with acute non ST elevation myocardial infarction (NSTEMI). Methods: 120 patients with NSTEMI were randomly divided into the combined treatment group (60 cases) and the control group (60 cases). The control group was treated with clopidogrel alone; the combined treatment group was treated with aspirin and clopidogrel. The serum levels of IL-1 β, IL-6, TNF - α and hs CRP in the two groups were measured. The changes of LVESD, LVDD, LVEF, LVEDV and LVESV in the two groups were monitored and compared. Results: Combined use of aspirin and clopidogrel can play a synergistic role in the treatment of NSTEMI patients, which is worthy of clinical application. Conclusion: The combination of bayaspirin and statins can play a synergistic role in the treatment of NSTEMI, which is worthy of clinical application.