目的：通过3D打印研究OSA患者的下颌骨异常表现，为术前诊断、手术设计提供理论依据。方法：采用3D打印技术制作24例已行上气道软组织手术的OSA患者下颌骨模型及24例正常人的下颌骨模型，测量下颌骨相关数据，统计分析两组测量指标的差异，并与AHI、LSaO2做Pearson线性相关分析。结果：OSA组与正常对照组数据比较下颌体夹角角度、下颌体长度、b线、a线/b线比值差异有统计学意义（P<0.05），其中，a线/b线比值与AHI、LSaO2相关性有统计学意义（P<0.05）。结论： 3D打印对OSA患者上颌骨结构异常评估具有重要参考价值。

Objective : 3D Printing was used to study the abnormal manifestations of the mandible of OSA patients, it will provide theoretical basis for preoperative diagnosis and surgical design. Methods Mandibular models of 24 patients with OSA who had undergone the surgery of upper airway’s soft tissue and 24 normal mandibular models were made by 3D Printing. Mandible-related data were measured, and the differences between the two groups of measurements were statistically analyzed ,then did Pearson correlation analysis with apnea hypoventilation index(AHI)；lowest oxygen saturation(LSaO2). Results The difference between the angle of mandibular body angle, the length of mandibular body, b-line, a- line / b-line ratio of OSA group and normal control group was statistically significant (P<0.05). The ratio of a- line /b-line with AHI, LSaO2 have statistically significant(P<0.05).Conclusion 3D Printing has important reference value for the evaluation of maxillary structural abnormalities in OSA patients.

内蒙古医科大学青年创新“鼾症患者下颌骨形态的数字化研究”(项目编号：YKD2016QNCX027)