目的：揭示RDW和Lp-PLA2对冠心病心绞痛急诊PCI术后近期不良心血管事件的预测价值。方法：2016年1月至2018年6月期间,选择我院收治的80例冠心病心绞痛患者作为研究对象,根据测得的红细胞分布宽度(RDW)和脂蛋白相关磷脂酶A2 (Lp-PLA2)中位数将患者分为高水平组和低水平组。分别比较两组PCI术后近期不良心血管事件发生率,并应用受试者工作特征曲线 (ROC)评价RDW和Lp-PLA2对冠心病心绞痛PCI术后不良血管事件的预测价值。结果：所有患者的RDW水平为10.10%～16.80%,中位数为13.3%,所有患者的Lp-PLA2水平为57～645 ng/mL,中位数为348 ng/mL。RDW高水平组的不良心血管事件发生率(13例,29.55%)显著高于低水平组(4例,11.11%)(χ²=4.021,p=0.045)。Lp-PLA2高水平组的不良心血管事件发生率(13例,31.71%)显著高于低水平组(4例,10.26%)(χ²=5.496,p=0.019)。RDW单独诊断的AUC为0.808,最佳截断值为15.15%,敏感度为0.647,特异性为0.873；Lp-PLA2单独诊断的AUC为0.817,最佳截断值为445.5 ng/mL,敏感度为0.706,特异性为0.857；ROD和Lp-PLA2联合诊断的AUC为0.821,最佳截断值处的敏感度为0.765,特异性为0.857。结论：RDW和Lp-PLA2水平越高,冠心病心绞痛PCI术后不良血管事件的发生率越高。RDW和Lp-PLA2联合检测对PCI术后不良血管事件具有较好的预测价值。

OBJECTIVE: To reveal the predictive value of RDW and Lp-PLA2 for short-term adverse cardiovascular events in patients with coronary heart disease and angina pectoris after emergency PCI. Methods: From January 2016 to June 2018, 80 patients with coronary heart disease and angina pectoris admitted to our hospital were selected as subjects. Patients were divided into high-level group and low-level group according to the median of red blood cell distribution width (RDW) and lipoprotein-associated phospholipase A2 (Lp-PLA2). The incidence of adverse cardiovascular events in the two groups after PCI was compared, and the receiver operating characteristic curve (ROC) was used to evaluate the predictive value of RDW and Lp-PLA2 for adverse vascular events after PCI in patients with coronary heart disease and angina pectoris. Results: All patients had an RDW level of 10.10%~16.80% with a median of 13.3%. All patients had a Lp-PLA2 level of 57~645 ng/mL with a median of 348 ng/mL. The incidence of adverse cardiovascular events in the high-level RDW group (n=13, 29.55%) was significantly higher than that in the low-level group (n=4, 11.11%) (χ2=4.021, p=0.045). The incidence of adverse cardiovascular events in the high-level Lp-PLA2 group (n=13, 31.71%) was significantly higher than that in the low-level group (n=4, 10.26%) (χ2=5.496, p=0.019). The AUC of RDW alone was 0.808, the optimal cut-off value was 15.15%, the sensitivity was 0.647, and the specificity was 0.873. The AUC of Lp-PLA2 alone was 0.817, the optimal cut-off value was 445.5 ng/mL, the sensitivity was 0.706, and specificity was 0.857; the AUC of the combined diagnosis of ROD and Lp-PLA2 was 0.821, the sensitivity at the optimal cut-off value was 0.765, and the specificity was 0.857. Conclusion: The higher the level of RDW and Lp-PLA2, the higher the incidence of adverse vascular events after PCI in patients with coronary heart disease and angina pectoris. The combined detection of RDW and Lp-PLA2 has a good predictive value for adverse vascular events after PCI.