目的 探讨腹膜透析对终末期肾脏病患者钙磷代谢、炎症因子及营养状态的影响。方法 回顾2016年5月-2018年3月我院收治的终末期肾脏病患者68例，将患者随机分为两组，对照组应用血液透析治疗，研究组应用腹膜透析治疗，分析两种透析方式对患者钙磷代谢以及炎性因子的影响。结果 研究组甲旁激素相关肽（213.4±250.3）pg/ml、血磷（1.3±0.5）mmol/L水平明显低于对照组甲旁激素相关肽（316.5±282.3）pg/ml、血磷（1.9±1.1）mmol/L（P＜0.05），研究组校正钙、钙磷乘积与对照组无明显差异（P＞0.05）；研究组CRP（18.3±3.5）mg/L的上升水平明显低于对照组CRP（24.1±3.6）mg/L（P＜0.05）；研究组心律失常、感染、高血压、低蛋白血症以及充血性心力衰竭等并发症发生率低于对照组（P＜0.05）；研究组营养不良发生率为64.7%，对照组营养不良发生率为82.4%，研究组营养状态优于对照组（P＜0.05）。结论 在针对终末期肾脏病患者进行治疗的过程中，腹膜透析的治疗方式对患者钙磷代谢、炎症反应程度以及营养状态的影响程度更小，可以有效降低并发症的发生，应当在临床上进行进一步的推广应用。

objective to explore the effects of peritoneal dialysis on calcium and phosphorus metabolism, inflammatory factors and nutritional status in patients with end-stage renal disease. Methods a total of 68 patients with end-stage renal disease admitted to our hospital from May 2016 to March 2018 were selected and randomly divided into two groups. The control group was treated with hemodialysis and the study group was treated with peritoneal dialysis. The effects of the two dialysis methods on calcium and phosphorus metabolism and inflammatory factors of the patients were analyzed. Results the parathyrosin (213.4±250.3) pg/ml and serum phosphorus (1.3±0.5) mmol/L levels in the study group were significantly lower than those in the control group (316.5±282.3) pg/ml and serum phosphorus (1.9±1.1) mmol/L (P < 0.05). The increased levels of CRP (18.3±3.5) mg/L in the study group were significantly lower than those in the control group (24.1±3.6) mg/L(P < 0.05). The incidence of complications such as arrhythmia, infection, hypertension, hypoproteinemia and congestive heart failure was lower in the study group than in the control group (P < 0.05). The incidence of malnutrition was 64.7% in the study group and 82.4% in the control group, and the nutritional status of the study group was better than that of the control group (P < 0.05). Conclusion in the course of treatment for patients with end-stage renal disease, the treatment method of peritoneal dialysis has less influence on calcium and phosphorus metabolism, inflammatory reaction degree and nutritional status of patients, which can effectively reduce the occurrence of complications and should be further promoted and applied in clinical practice.