目的 分析男性非小细胞肺癌的临床特征及其淋巴结转移的危险因素,旨在及时确定易发生淋巴结转移的高危人群,为临床治疗方案的制定提供客观数据支持。方法 回顾性分析2018年3月至2019年10月本院收治的127例经病理检查确诊的男性非小细胞肺癌患者127例临床资料,根据术后病理检查结果,将发生淋巴结转移的24例患者纳入转移组,将其余未发生转移的103例患者纳入未转移组,设计一般情况调查表,仔细查阅患者病历资料,详细记录患者一般资料(年龄、吸烟、临床症状等)、肿瘤直径、血清癌胚抗原(CEA)、肿瘤位置、肿瘤分布、病理类型、分化程度等相关数据。分析男性非小细胞肺癌临床特征,并经单因素与多因素分析找出可能影响男性非小细胞肺癌发生淋巴结转移的危险因素。结果 男性非小细胞肺癌多发于45岁以上中年男性群体,占比约为63.78%；无明显临床症状占比最高,呼吸困难及体重下降次之；肿瘤类型及病理分型中以周围型及腺癌占比最高；左上肺为发病率最高部位,右上肺次之；经非条件多项Logistic回归分析显示,直径较大、CEA水平较高及分化程度低可能是影响男性非小细胞肺癌患者淋巴结转移的危险因素(OR＞1,P＜0.05)。结论 男性非小细胞肺癌多发于中年人群,发病症状不显著,多呈周围型,多为腺癌且左肺占比最高；肿瘤直径大、CEA高表达及低分化可能是诱发淋巴结转移的危险因素,故术前诊断中应密切观察上述影响因素,以做出准确判断,为治疗方案的制定提供依据。

objective to analyze the clinical characteristics of male non-small cell lung cancer (NSCLC) and the risk factors of lymph node metastasis in order to identify the high risk population prone to lymph node metastasis in time and to provide objective data support for the formulation of clinical treatment plan. Methods the clinical data of 127 male patients with non-small cell lung cancer diagnosed by pathological examination from March 2018 to October 2019 were analyzed retrospectively. according to the results of postoperative pathological examination, 24 patients with lymph node metastasis were included in the metastasis group and 103 patients without metastasis were included in the non-metastasis group. The general data (age, smoking, clinical symptoms, etc.), tumor diameter, serum carcinoembryonic antigen (CEA), tumor location, tumor distribution, pathological type, differentiation degree and other related data were recorded in detail. The clinical features of male non-small cell lung cancer were analyzed, and the risk factors of lymph node metastasis in male non-small cell lung cancer were identified by univariate and multivariate analysis. Results most of male non-small cell lung cancer (NSCLC) occurred in middle-aged men over 45 years old, accounting for 63.78%. The proportion of non-small cell lung cancer (NSCLC) was the highest in male population over 45 years old, followed by dyspnea and weight loss, and tumor type and pathological classification. Logistic regression analysis showed that large diameter, high CEA level and low differentiation might be the risk factors for lymph node metastasis in male patients with non-small cell lung cancer (OR > 1, P < 0.05). Conclusion male non-small cell lung cancer is more common in middle-aged population, the symptoms are not significant, most of them are surrounding type, most of them are adenocarcinoma and the proportion of left lung is the highest. Large tumor diameter, high expression of CEA and low differentiation may be the risk factors of lymph node metastasis. Therefore, the above effects should be closely observed in preoperative diagnosis. Factors, in order to make accurate judgment, for the formulation of treatment plan to provide the basis.