【摘要】目的 探讨应用窄带成像内镜技术（narrow band imaging,NBI）筛查喉部增生性病变的临床意义。方法 选择2017年6月至2019年10月期间在内蒙古自治区人民医院因喉部增生性病变接受手术治疗的患者187例，术前行电子喉镜下白光成像检查和NBI成像检查并作出初步诊断，之后在全麻支撑喉镜下显微镜下行喉部病变切除术，将切除组织行病理检测，并以病理诊断为标准，比较电子喉镜两种观察模式对喉部病变的诊断符合率，评价NBI对喉部良恶性病变筛查的意义，同时观察并总结NBI成像下喉腔各类病变的微血管形态特征。结果 在病理参照下，187例患者白光成像的诊断符合率为76.47%（143/187），而NBI成像的诊断符合率为90.91%（170/187），两者差异具有统计学意义（P<0.05）；对于36例恶性病变组，白光成像的诊断符合率为75.00%（27/36），而NBI成像的诊断符合率为94.44%（34/36），两者差异具有统计学意义（P<0.05）。结论 由于NBI在识别粘膜表面微细血管形态变化方面较白光内镜有更多的优势，将其应用于喉部增生性病变的筛查，对于提高喉部恶性病变的早期诊断率将更有帮助。

【Abstract】 Objective To explore the clinical significance of narrow-band imaging endoscopy in the screening of laryngeal hyperplastic lesions. Methods From June 2017 to October 2019, 187 patients who received surgical treatment for laryngeal hyperplasia in the people''s Hospital of Inner Mongolia Autonomous Region were selected. Before surgery，the patients were examined and diagnosed by white light and NBI endoscopy. Then they were underwent microscopic resection of laryngeal lesions under general anesthesia by supporting laryngoscope . Pathological examination was performed on the excised tissue. Based on the pathological diagnosis, the coincidence rate of the two observation modes of electronic laryngoscope in the diagnosis of laryngeal diseases was compared. The significance of NBI for the screening of laryngeal hyperplastic lesions and malignant lesions was evaluated, and the microvascular morphological features of laryngeal lesions under NBI imaging were observed and summarized . Results Under pathological reference, in 187 patients , the diagnostic accordance rate was76.47%（143/187） for white light imaging, while 90.91%（170/187） for NBI ; In 36 malignant lesions, the diagnostic accordance rate was 75.00%（27/36） for white light imaging , while 94.44%（34/36）for NBI . The laters were significantly higher than the formers, and their differences were statistically significant (P<0.05) . Conclusion NBI has more advantages than white light endoscopy in identifying the changes of microvascular morphology on mucosal surface。Its application in the screening of laryngeal hyperplastic lesions is beneficial to improve the accuracy of early diagnosis of malignant lesions of laryngeal cavity.