[关键词]
[摘要]
胃癌(Gastric cancer)是我国最常见的消化道肿瘤之一。近几年，胃癌早期诊断以及低副作用的有效治疗已经成为研究人员重点关注的方向和领域。噬菌体展示肽库技术 (phage display library, PDL)作为分析蛋白质之间相互作用的有效方法，具有简便、高效、高通量等优点，这使得PDL在胃癌的诊断检测和靶向治疗领域展示出了极大的研究价值和潜力。本文就目前PDL技术在胃癌诊断和治疗领域中的研究进展进行综述。
[Key word]
[Abstract]
Gastric cancer is one of the most common deadly tumors in China. Researches on gastric cancer mainly focus on early diagnosis and effective treatment with low side effects. Phage display library technology (PDL), as an efficient and convenient tool for studying the interaction mechanism between proteins, has a great prospect in the field of early diagnosis and targeted therapy of gastric cancer. In this review, we will focus on the progress and application of the detection and treatment in gastric cancer.
[中图分类号]
[基金项目]
生物活性肽联合奥沙利铂下调TPX2治疗胃癌增敏分子作用机制研究
