目的 比较在容量负荷和压力负荷下每博量变异性(SVV)和中心静脉压(CVP)的反应性。方法 选择30例择期口腔正颌手术患者,随机将其分为容量负荷组(VL组)和压力负荷组(PL组)。记录VL组诱导前心率（HR，heart rate）, 动脉血压（ABP，arterial blood pressure），(本研究记录动脉收缩压SBP)、心输出量（CO，cadiac output）、SVV、CVP各项血流动力学数值(Tb)，诱导后行控制性降压至血压低于基础水平70%时记为T0。分别在不同时间点记录以上数值。PL组从右股静脉泵注去氧肾上腺素，至血压为基础值80%停止泵注，同样在上述时间点记录。结果 VL组每博量变异度(SVV)在15min，20min时显著减少，CVP有上升趋势但无明显统计学意义； PL组SVV及CVP均无明显变化。 结论 在相对低血容量状态下，随着循环容量增加SVV明显降低，CVP无显著变化；使用血管活性药物令后负荷增加对SVV及CVP均无明显影响。

Objective Comparing the sensibility of SVV with CVP in patients undergoing volume and pressure loading. Methods HR, ABP, CO, SVV, CVP numerical inhemodynamic of 30 patients were redorded before induction. (Tb). Maintaining stable blood pressure during operation. Patients in VL group received 6% hydroxyethyl starch infusion when patient"s BP was 70% below base value. SVV, CVP and other hemodynamic parameters were obtained at different time after volume or pressure loading. Results There was significant decrease in the value of SVV at 15min and 20min in VL group. Conclusion SVV significantly decreased as circulating volume increased in hypovolemia patients.