目的：急性腹泻是儿科常见的一种症状，它背后的成因很复杂，其中常见的原因是轮状病毒感染，若不 及时治疗危害较大。常用的治疗方法包括蒙脱石散以及包括酪酸梭菌二联活菌在内的益生菌治疗，而两者的结合疗 法是否比单独使用蒙脱石散更加有效还有待讨论，本荟萃分析旨在探讨该联合用药的有效性。方法：在本研究中共 计纳入7个临床实验，共计联合用药受试者513名，单药蒙脱石散受试者485名，均为儿科急性腹泻患者。结果：显示 联合用药有效率强烈显著优于单独使用蒙脱石散，而双药组平均减少腹泻持续时间为-0.51。结论：该联用治疗儿童 急性腹泻相对于单药蒙脱石散更加有效。

Objective：Acute diarrhea is a common symptom in pediatrics. The causes behind it are very complex, among which the common cause is rotavirus infection, which is more harmful if not treated in time. While it remains to be seen whether a combination of montmorillonite and probiotics, including clostridium caseinate, which are commonly used, is more effective than a combination of the two, this meta-analysis aims to investigate the effectiveness of the combination. Methods: A total of 7 clinical trials were included in this study, including a total of 513 subjects with combined drug and 485 subjects with single drug montmorillonite powder, all of whom were pediatric patients with acute diarrhea. Results: The effective rate of combined drug was significantly higher than that of montmorillonite powder alone, and the average duration of diarrhea was -0.51 in the double-drug group. Conclusion: The combined treatment of acute diarrhea in children is more effective than montmorillonite powder alone.