目的：系统评价中西医结合治疗面部脂溢性皮炎的临床疗效以及对皮肤屏障功能的影响；方法：计算机检索CNKI、VIP、CBM、万方四个数据库中关于中西医结合治疗面部脂溢性皮炎的RCT文献,对纳入文献采用Cochrane评价手册中RCT质量评价工具进行质量评价,提取有效率、症状积分、皮肤生理参数指标等数据,采用RevMan软件进行Meta分析；结果：共纳入文献12篇,患者1260例。Meta分析显示：中西医结合治疗组疗效明显优于单纯西医组,差异具有统计学意义(RR=1.17,95%CI为1.11～1.22,Z=6.41,P<0.05)。同时,从症状积分、皮肤生理参数指标、复发率和不良反应发生率来看,差异也有统计学意义；结论：中西医结合能显著改善面部脂溢性皮炎患者临床症状,快速恢复面部皮肤屏障功能,安全可靠且复发率低,非常值得在临床中广泛推广。

Objective: To systematically evaluate the clinical efficacy of traditional Chinese and Western medicine in the treatment of facial seborrheic dermatitis and its effect on the skin barrier function. Methods: We retrieved lots of RCT literature on how traditional Chinese and Western medicine treat the facial seborrheic dermatitis from four databases(CNKI;VIP;CBM and WanFang data).As for selected literature ,we use RCT quality evaluation tool of Cochrane handbook to evaluate their quality .Then we extract some data such as efficiency, symptom integrals, skin physiological parameters, etc. from the literature and use Revman software to Meta analysis. Results: 12 literature is referred including 1260 patients. According to Meta-analysis, the clinical efficacy of traditional Chinese and Western medicine groups was better than that of Pure-Western medicine significantly(RR=1.17,95%CI为1.11～1.22,Z=6.41,P<0.05). At the same time, the differences were statistically significant in terms of symptom integrals, skin physiological parameters, recurrence rate and incidence of adverse reactions. Conclusion：Traditional Chinese and Western medicine can significantly improve the efficiency of the treatment of facial seborrheic dermatitis. And the treatment is safe and has low relapse rate which can efficiently improve the function of the skin barrier. So it can be widely used in clinical treatment.