目的：探讨不同性别、年龄对脊柱压缩性骨折患者睡眠质量与生活质量的影响。方法：选取100例脊柱压缩性骨折为研究对象，根据性别不同分为男性组48例，女性组52例；根据不同年龄分为3组，分别为≤40岁组27例、40~60岁组34例、≥60岁组29例。分别采用匹兹堡量表（(Pittsburgh sleep quality index，PSQI）、中文版SF-36量表（the MOS item short from health survey，SF-36）评估不同性别、年龄患者在骨折前、骨折后第4周的睡眠质量及生活质量。结果：骨折后第4周男性组、女性组睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能障碍、PSQI总分均高于同组骨折前，组内差异（P＜0.05）；骨折后第4周，女性组睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能障碍、PSQI总分均高于同条目男性组，组间差异（P＜0.05）。骨折后第4周男性组、女性组PF、RP、BP、VT、SF、RE 、MH、GH评分，组内差异（P＜0.05）；骨折后第4周女性组PF、RP、BP、VT、SF、RE 、MH、GH评分均低于同条目男性组，组间差异（P＜0.05）。随年龄增长，睡眠质量中除睡眠时间外，其余均总体呈下降趋势；PF、RP、BP、VT、SF、RE 、MH、GH评分呈下降趋势，组间差异（P＜0.05）；3组除睡眠时间、日间功能障碍外，骨折第4周其余睡眠项目指标评分均高于同组同组骨折前，组内差异（P＜0.05）；除睡眠时间、日间功能障碍外，≤40岁组、40~60岁组、≥60岁组其余睡眠项目指标增值评分呈增加趋势，组间差异（P＜0.05）。≤40岁组、40~60岁组、≥60岁组PF、RP、BP、VT、SF、RE 、MH、GH增值评分无明显改变，组间差异（P＞0.05）。结论：脊椎压缩性骨折后，男女睡眠质量及生活质量总体均下降，以女性更甚；年龄越大，患者睡眠质量与生活质量越差，睡眠质量总体与年龄呈正比，而生活质量在不同年龄阶段改变的差异性不明显。

Objective: To investigate the effect of spinal compression fracture on sleep quality and quality of life in patients of different gender and age. Methods: 100 cases of compression fracture of spine were selected as the research object, according to the gender, 48 cases were divided into male group and 52 cases into female group. According to the age, they were divided into three groups: 27 cases in the group of ≤ 40 years old, 34 cases in the group of 40-60 years old and 29 cases in the group of ≥ 60 years old.The Pittsburgh sleep quality index (PSQI) and the Chinese version of the MOS item short from health survey (sf-36) were used to evaluate the sleep quality and quality of life of patients of different genders and ages before and 4 weeks after fracture. Results: the scores of sleep quality, sleep time, sleep time, sleep efficiency, sleep disorders, hypnotics, daytime dysfunction and PSQI in the male and female groups were higher than those in the same group at the 4th week after fracture (P < 0.05); the scores of sleep quality, sleep time, sleep time, sleep efficiency, sleep disorders, hypnotics and daytime in the female group at the 4th week after fracture were higher than those before fracture (P < 0.05) The total score of dysfunction and PSQI was higher than that of the same item in male group (P < 0.05). The scores of PF, RP, BP, VT, SF, re, MH, GH in the male and female groups at the 4th week after fracture were lower than those in the male group (P < 0.05). With the increase of age, except the sleep time, the rest of the sleep quality showed a general downward trend; PF, RP, BP, VT, SF, re, MH, GH scores showed a downward trend, the difference between the groups (P In addition to daytime dysfunction, the value-added scores of other sleep items in the groups of 40-60 years old or over 60 years old showed an increasing trend (P < 0.05). There was no significant difference in PF, RP, BP, VT, SF, re, MH, GH value-added scores among the groups of 40-60 years old or over (P > 0.05). Conclusion: After compression fracture of spine, the sleep quality and life quality of both men and women decreased, especially women. The older the patients, the worse the sleep quality and life quality, and the sleep quality was in direct proportion to age, but the difference of life quality in different age stages was not obvious.