[关键词]
[摘要]
在我国腰椎间盘突出症等骨关节退行性疾病已成为中老年人群中的常见病和多发病,给社会造成沉重的经济负担。内蒙古特色蒙药那如三味丸在治疗腰椎间盘突出症等骨关节退变性疾病中取得良好效果,但是具体的药物作用机制还有待明确。网络药理学是依托于系统生物学发展而来的新型学科,其系统性、多效性、多靶点出发分析药物药理作用的特点非常适用于中药、蒙药、藏药等传统复方方剂的药理机制、作用靶点以及相关通路的研究。本文就近年来网络药理学用于中药、蒙药、藏药的药理机制研究做一综述。
[Key word]
[Abstract]
In China, bone and joint degenerative diseases such as lumbar disc herniation have become common and frequently-occurring diseases in the middle-aged and elderly, causing a heavy economic burden to the society. Inner Mongolia characteristic Mongolian medicine Naru Sanwei Pill has achieved good results in the treatment of bone and joint degenerative diseases such as lumbar disc herniation, but the specific drug mechanism remains to be determined. Network pharmacology is a new discipline based on the development of system biology. its systematic, multi-effect and multi-target analysis of the characteristics of drug pharmacology is very suitable for the study of pharmacological mechanism, action targets and related pathways of traditional compound prescriptions such as traditional Chinese medicine, Mongolian medicine, Tibetan medicine and so on. This paper reviews the pharmacological mechanism of network pharmacology in traditional Chinese medicine, Mongolian medicine and Tibetan medicine in recent years.
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[基金项目]