【摘要】目的：袖式肺叶切除术与患侧全肺切除对非小细胞肺癌患者疗效、并发症及癌胚抗原（CEA）、糖类抗原125（CA125）水平的影响比较。方法：分析2015年8月~2018年8月期间本院收治的86例非小细胞肺癌患者临床资料，44例行患侧全肺切除，将其作为对照组，42例行袖式肺叶切除术，将其作为研究组。对比短期疗效与术后1年存活率，测定CEA、CA125水平，并统计并发症发生情况。结果：研究组缓解率与术后1年存活率均高于对照组（P＜0.05）；术后测定2组CEA、CA125水平均较术前下降（P＜0.05），且研究组术后CEA、CA125水平明显低于对照组（P＜0.05）；研究组并发症总发生率低于对照组（P＜0.05）。结论：与患侧全肺切除相比，应用袖式肺叶切除术治疗非小细胞肺癌短期疗效更可靠，术后1年生存率更高，CEA、CA125水平更合理，并发症发生概率更低。

[Abstract] Objective To compare the effects of sleeve lobectomy and pneumonectomy on the curative effect, complications, CEA levels and CA125 levels in patients with non-small cell lung cancer. Methods The clinical data of 86 patients with non-small cell lung cancer admitted to our hospital from August 2015 to August 2018 were analyzed, pneumonectomy was performed in 44 patients as control group, and sleeve lobectomy was performed in 44 patients as study groups. The short-term efficacy was compared with the 1-year survival rate, CEA and CA125 levels were measured, and complications were counted. Results Remission rate and 1-year survival rate in the study group were higher than those in the control group (P<0.05); The CEA and CA125 levels in both groups were decreased after operation (P<0.05), and the CEA and CA125 levels in the study group were significantly lower than those in the control group (P<0.05); The total incidence of complications in the study group was lower than that in the control group (P<0.05). Conclusion Sleeve lobectomy is more reliable in the treatment of non-small cell lung cancer in the short term than total pneumonectomy, and the 1-year survival rate of Sleeve lobectomy was higher than that of total pneumonectomy, the CEA and CA125 levels were more reasonable, and the incidence of complications was lower.