勃起功能障碍(ED)是成年男性最常见的一种性功能障碍，发病率随着男性的年龄增长而增高，严重影响了患者的生活质量。许多因素可以引起ED，但其具体的发病机制仍未完全清楚。ED按病因分为精神心理性、器质性及混合性三大类。近年来血管性ED引起了较多的关注。随着研究的深入，发现许多慢性疾病，如心血管、内分泌、呼吸系统等疾病的过程中均会出现血管内皮细胞的损伤，同时这些慢性病患者的ED发病率也较对照组高。目前，有关慢性病患者ED为何发生率高，原因尚不完全清楚，不少的报道显示血管性因素是主要原因。本文就临床上常见的一些慢性疾病对血管性ED影响的研究进展做一综述。

Erectile dysfunction (ED) is the most common sexual dysfunction in adult men，its incidence increases with the age of men, which seriously affects the quality of life of patients. Many factors can cause ED, but its specific pathogenesis is still not fully understood. According to the etiology, ED can be divided into three categories: psychosomatic, organic and mixed. Vascular ED has attracted more attention in recent years. With the deepening of research, it is found that vascular endothelial cells would be damaged in the process of chronic diseases of various systems, and the incidence of ED in these patients with chronic diseases is also higher than that in the control group. At present, the reasons for the high incidence of ED in patients with chronic diseases are not fully understood,but many reports indicate that vascular factors are the main cause. This article reviews the research progress of the impact of some common clinical diseases on vascular ED.