：目的:探讨我区生活环境因素对非小细胞肺癌（NSCLC）的影响，为我区预防NSCLC提供参考。方法：收集2017年9月至2019年7月，在内蒙古医科大学附属医院进行外科手术治疗的原发性非小细胞肺癌患者入组的244例和在内蒙古医科大学附属医院进行接受体检的健康个体入组的268例。问卷调查对象的一般人口学特征、吸烟暴露情况和室内空气污染暴露情况、饮酒情况、饮食习惯。采用卡方检验、logistic回归分析进行统计分析与肺癌易感性的关系。结果：本次研究纳入调查对象病例组和对照组年龄（χ2=2.34，P=0.310）、性别（χ2=0.43,p=0.513）、婚姻状况（χ2=1.46，P=0.480）、文化程度（χ2=4.07，P=0.254）、职业（χ2=3.01，P=0.390）、油烟暴露（χ2=1.18，P=0.276）、蔬菜类（χ2=2.89，P=0.236）及奶类（χ2=0.18，P=0.668）差异无统计学意义。卡方检验发现BMI（χ2=6.02，P=0.049）、居住地（χ2=41.56，P<0.001）、吸烟（χ2=74.38，P<0.001）、被动吸烟（χ2=7.03，P=0.008）、蛋类（χ2=0.79，P=0.007）与非小细胞肺癌有关联性。结论： BMI、吸烟、被动吸烟、饮酒和蛋类是非小细胞肺癌的影响因素。提示我们，今后应针对相关的环境影响因素开展预防性的干预措施，从而有效预防非小细胞肺癌的发病风险。

Objective: to explore the influence of living environment factors on non-small-cell Lung Carcinoma in our district, and to provide reference for the prevention of NSCLC in our district. Methods: From October 2017 to July 2019, 244 patients with primary non-small cell lung cancer underwent surgical treatment in the Affiliated Hospital of Inner Mongolia Medical University and 268 healthy individuals underwent physical examination in the Affiliated Hospital of Inner Mongolia Medical University. The general demographic characteristics, exposure to smoking and indoor air pollution, drinking and eating habits of the subjects were investigated. Chi-square test and Logistic regression analysis were used to analyze the relationship between lung cancer susceptibility and statistical analysis. Results: Age (χ2=2.34, P=0.310), gender (χ2=0.43, P= 0.513), marital status (χ2=1.46, P=0.480), educational level (χ2=4.07, P=0.254), occupation (χ2=3.01, χ2=3.01) were included in the case group and the control group. P=0.390), lampblack exposure (χ2=1.18, P=0.276), alcohol consumption (χ2=3.74, P=0.154), vegetables (χ2=2.89, P=0.236) and milk (χ2=0.18, P=0.668) had no significant differences. Chi-square test showed BMI (χ2=6.02, P=0.049), place of residence (χ2=41.56, P<0.001), smoking (χ2=74.38, P<0.001), passive smoking (χ2=7.03, P=0.008), eggs (χ2=0.79, P=0.007) was associated with non-small cell lung cancer. Conclusion: BMI, smoking, passive smoking, alcohol consumption and eggs are risk factors for NSCLC. It is suggested that preventive intervention measures should be carried out for related environmental factors in the future, so as to effectively prevent the risk of NSCLC.

内蒙古医科大学附属医院重点科研项目(NYFY ZD 015)