SPECT是核医学中的一种重要成像仪器。常规的平行孔准直器-SPECT设备通过旋转双探头以实现断层成像功能,由于其灵敏度低、空间分辨率低以及采集时间长,致使图像质量大幅度降低。近年来,IQ-SPECT以及采用固态碲?锌?镉(CZT)晶体作为探测器的新型心脏专用SPECT已应用于临床,其灵敏度、特异性和准确性均优于平行孔准直器-SPECT,但CZT-SPECT成本太高。新型多针孔准直器(MPH)不仅可以搭载在普通SPECT机上,还能够在达到心脏专用CZT-SPECT性能的同时明显降低成本。本文将对不同准直器的SPECT设备在心肌成像中的应用及进展进行综述。

SPECT is an important imaging instrument in nuclear medicine. The conventional parallel-hole collimator-SPECT device realizes tomographic imaging function by rotating dual probes. Due to its low sensitivity, low spatial resolution and long acquisition time, the image quality is greatly reduced. In recent years, IQ-SPECT and a new type of cardiac-specific SPECT using solid-state tellurium-zinc-cadmium (CZT) crystals as detectors have been used in clinical practice, and its sensitivity, specificity and accuracy are better than parallel hole collimator-SPECT. But the cost of CZT-SPECT is too high. The new multi-pinhole collimator (MPH) can not only be mounted on an ordinary SPECT machine, but also can achieve the performance of the heart-specific CZT-SPECT while significantly reducing costs. This article will review the application and progress of SPECT equipment with different collimators in myocardial imaging.

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