目的：总结和分析2018-2019年呼和浩特市自然人群大肠癌早期筛查的效果,探讨筛查过程中出现的问题,为推动社区早癌筛查工作提供指导。方法：调查2018年5月1日-2019年4月30日在内蒙古医科大学附属医院体检中心参检的呼和浩特市居民,通过宣传教育、问卷病史调查和数值化免疫定量粪便潜血试验(fecal occult blood tests,FOBT)检测开展大肠癌筛查。结果：共完成初筛10741人,男5263例,女5478例,年龄18-87岁。FOBT检查结果阳性559例,初筛完成率为 99%,初筛阳性率为5.2%。高危人群中肠镜检查阳性率为14.67%,大肠癌检出率为0.89%。总大肠癌检出率为46.55/10万。结论：FOBT对早期发现和诊断大肠癌及其癌前病变具有重大意义,普及中国体检人群大肠癌早期筛查是健康中国的重要步骤。

Abstract: Objective Summarizing and analyzing the effectiveness of early screening for Colorectal Cancer in Hohhot population in 2018 -2019，exploring the problems in the process of screening，to provide guidance for early cancer screening in the community。 Methods The residents of Hohhot population were investigated from 2018.5.1-2019.4.30 in the physical examination center of Affiliated Hospital of Inner Mongolia Medical University，colorectal cancer screening was carried out through publicity and education, questionnaire survey of medical history and FOBT detection Results A total of 10741 patients, of 5263 males and 5478 females, aged 18-87。FOBTpositive 559 cases， the completion rate is 99%, the positive rate of primary screening was 5.2%. The enteroscopepositive rate was 14.67%, The detection rate of colorectal cancer was 0.89%.the overall detection rate of colorectal cancer was 46.55parts per 100,000. Conclusion FOBT is of great significance in the early detection and diagnosis of colorectal cancer, universal screening for colorectal cancer in Chinese population is an important step in healthy China.

2019年内蒙古自治区自然科学基金(2019MS08147)