纳米二氧化钛发展迅速，因其极高的稳定性、防腐和光催化性能而被广泛使用，目前已渗透到生产生活各个领域，如制药、化妆品、医学、生物学、生物技术、农业、工程和工业等。然而，纳米技术是一把双刃剑。纳米材料在发挥其优点的同时也作为紧急污染物负面影响着周围环境和人类的健康，因其可以在生物体内富集，迫切需要阐释其对人类健康的潜在副作用。纳米二氧化钛的长期单独或联合使用均存在神经毒性、肝脏毒性等生物毒性，各类毒性不同程度地危害正常细胞或器官，最终影响人体健康。本文主要探讨纳米二氧化钛对于各个脏器的毒性研究，为其在医学的应用中提供科学依据。

Nano-titanium dioxide has developed rapidly and is widely used due to its extremely high stability, anti-corrosion and photocatalytic properties. It has now penetrated into various fields of production and life, such as pharmacy, cosmetics, medicine, biology, biotechnology, agriculture, engineering and industry, etc. . However, nanotechnology is a double-edged sword. Nanomaterials not only exert their advantages, but also serve as emergency pollutants that negatively affect the surrounding environment and human health. Because they can be enriched in organisms, it is urgent to explain their potential side effects on human health. The long-term use of nano-titanium dioxide alone or in combination has biological toxicity such as neurotoxicity and liver toxicity. Various types of toxicity harm normal cells or organs to varying degrees, and ultimately affect human health. This article mainly discusses the toxicity study of nano-titanium dioxide to various organs, and provides scientific basis for its medical application.

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