目的 探究过敏性鼻炎（AR）发生的相关危险因素及干预策略。方法 选取我院95例AR患者作为AR组，另选同期95例健康志愿者作为对照组，统计比较两组一般资料，分析AR发生的影响因素。结果 AR组过敏史、吸烟史、鼻炎家族史、体育锻炼中无锻炼、哮喘占比均高于对照组，差异有统计学意义（P＜0.05）；过敏史、吸烟史、鼻炎家族史、哮喘均为AR发生的独立危险因素，体育锻炼为保护因素（P＜0.05）。结论 AR发生的危险因素主要为过敏史、吸烟史、鼻炎家族史、哮喘，体育锻炼为保护因素，对于存在以上危险因素者应加强AR健康教育，避免接触过敏源，提示加强体育锻炼，以降低AR发生风险。

Objective To explore the relevant risk factors and intervention strategies of allergic rhinitis (AR).Methods 95 AR patients were selected as AR group, and 95 healthy volunteers in the same period as control group to compare the general data of the two groups and analyze the influencing factors of AR.Results AR had higher proportion of allergy, smoking, rhinitis, physical exercise than control group (P <0.05); allergy, smoking, rhinitis and asthma were independent risk factors for AR and physical exercise was a protective factor (P <0.05).Conclusion The risk factors for AR are mainly allergic history, smoking history, family history of rhinitis and asthma, and physical exercise are protective factors. For those with the above risk factors, AR health education should be strengthened to avoid exposure to allergens, and suggest strengthening physical exercise to reduce the risk of AR.

运用LC-MC筛选出变应性鼻炎的特异性标志物及应用研究