目的：通过分析肺炎支原体肺炎患儿血清维生素A的水平、体液免疫蛋白的水平,并分析两者的相关性,探讨维生素A的临床意义。方法：筛选符合研究条件的2017年8月至2020年9月期间内蒙古医科大学附属医院儿科病房住院治疗的240例肺炎支原体肺炎患儿作为试验组,筛选同一时间段在本院儿科门诊就诊的240例非肺炎支原体感染的儿童作为对照组,通过比较两组之间血清维生素A的水平及体液免疫蛋白的水平,并分析两者之间有无相关性。结果：对照组血清维生素A水平明显高于试验组(P<0.05),对照组血清IgA水平明显高于试验组(P<0.05),肺炎支原体肺炎患儿血清维生素A水平与血清IgA水平呈正相关(P<0.05)。结论：血清维生素A水平与儿童肺炎支原体肺炎的发生具有相关性,与体液免疫蛋白水平具有相关性。

Purpose：To explore the clinical significance of vitamin A in children with mycoplasma pneumoniae pneumonia and normal children, the correlation between serum vitamin A and humoral immune protein was analyzed. Method：240 children with mycoplasma pneumoniae pneumonia treated in the Department of Pediatrics, affiliated Hospital of Inner Mongolia Medical University from August 2017 to September 2020 were selected as the experimental group, and 240 children who underwent physical examination in the outpatient were selected as the control group in the same period. The level of serum vitamin A was compared, and the correlation between serum vitamin A and humoral immune protein level was analyzed. Result：The serum vitamin A level in the test group was lower than that in the control group (P < 0.05), and the serum IgA level in the test group was lower than that in the control group (P < 0.05). The serum vitamin A level in children with mycoplasma pneumoniae pneumonia was positively correlated with the IgA level (P < 0.05). Conclusion：The level of serum vitamin A was correlated with the occurrence of mycoplasma pneumoniae pneumonia and humoral immune protein in children.

内蒙古自治区自然科学基金项目